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Braun Pulverizer Bcl 736 A Bcl2 Homolog Encoded By Kaposi Sarcomaassociated Jan 21, 1997 The Bcl-2 protein family is characterized by the ability to modulate cell death, and members of this family share two highly conserved domains called Bcl-2 homology 1 BH1 and 2 BH2 which have been shown to be critical for the death-repressor activity of Bcl ....

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Prostate cancer PCa is the most common cancer and the second-leading cause of cancer-associated death in men Siegel et al 2014 Because of the progress made in the treatment of the primary tumor, mortality in cancer patients is now increasingly linked to the metastatic disease Fig 1 Sleeman and Steeg 2010 PCa metastasizes to different organs with a propensity to bone Gandaglia et al ....

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Selected publications Nyangahu D, Lennard KS, Brown BP, Darby MG, Wendoh JM, Havyarimana H, Smith P, Butcher J, Stintzi A, Mulder N, Horsnell W, Jaspan HBDisruption of maternal gut microbiota during gestation alters offspring immunity...

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PUMA is a BH3 Bcl-2 homology domain 3 -only protein that induces apoptosis through the mitochondrial pathway The study of PUMA null mice showed that the induction of PUMA by p53 is necessary for the apoptotic response to p53 activation in many tissues Yu and Zhang, 2003...

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Braun Pulverizer Bcl 736 JAK/STAT signaling in stem cells and regeneration from The JAK/STAT pathway is a conserved metazoan signaling system that transduces cues from extracellular cytokines into transcriptional changes in the nucleus JAK/STAT signaling is best known for its roles in immunity However recent work has demonstrated that it ....

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Central and Peripheral Metabolic Defects Contribute to the , - Saber más

Apr 28, 2020 0183 32 Significance Epidemiological studies indicate that metabolic disorders are associated with an increased risk for Alzheimer s disease AD Metabolic remodeling occurs in the central nervous system CNS and periphery, even in the early stages of AD Mitochondrial dysfunction has been widely accepted as a molecular mechanism underlying metabolic disorders Therefore, focusing on early ....

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Nov 15, 2021 0183 32 Diabetes mellitus DM is a strong risk factor for the development of cardiovascular diseases such as coronary heart disease, cerebrovascular disease, and peripheral arterial disease PAD In the population of people living with DM, PAD is characterised by multi-level atherosclerotic lesions as well as greater involvement of the arteries below the knee DM is also a factor that ,...

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Subaru s EJ20G was a turbocharged, 20-litre horizontally-opposed or boxer four-cylinder petrol engine For Australia, the EJ20G engine powered the GC/GM Impreza WRX from 1994 to 1996 key features of the EJ20G engine included its Die-cast aluminium block and cylinder head...

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WEB ACCESSIBILITY OF MOOCS FOR ELDERLY STUDENTS THE , - Saber más

Learning, eLearning and distance education has a significant function on the elderly for advancing well-being, which has indicated in the literature In addition to this, e-learning provides an opportunity to become unified with the rest of society to older people In this context, older people have extensive opportunities to raise the qualified life and enable lifelong learning and inclusion ....

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Product Catalog B Braun offers products and product systems for anesthesia, intensive care, cardiology, extracorporeal blood treatment, and surgery, as well as providing services for clinics, and physicians in private practices, and for the home care sector In total, the B Braun product range includes 5,000 different products, 95 percent of ....

StarD13 a potential star target for tumor therapeutics , - Saber más

Apr 09, 2020 0183 32 StarD13 is a tumor suppressor and a GTPase activating protein GAP for Rho GTPas Thus, StarD13 regulates cell survival pathways and induces apoptosis in a p53-dependent and independent manners In tumors, StarD13 is either downregulated or completely inhibited, depending on the tumor type As such, and through the dysregulation of Rho GTPases, this affects adhesion ,...

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Marine natural products - Saber más

Abstract This review covers the literature published in 2019 for marine natural products MNPs , with 719 citations 701 for the period January to December 2019 referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms...

BDNF Acts as a Prognostic Factor Associated with Tumor , - Saber más

Nov 05, 2021 0183 32 Pancreatic adenocarcinoma PAAD is an extremely lethal disease worldwide Brain-derived neurotrophic factor BDNF is a critical member of the neurotrophin polypeptide superfamily that plays an important role in multiple cancers However, the association among BDNF expression, tumor immunity, and PAAD prognosis remains unclear BDNF expression and its influence on patient ,...

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Modulation of Autophagy A Novel Rejuvenation Strategy , - Saber más

Feb 10, 2021 0183 32 Modulation of autophagy is a promising strategy for rejuvenation of the aged liver Detailed knowledge regarding the most devastating processes in the individual patient is needed to effectively counteract aging of the liver without causing obvious harm 1 Introduction...